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Liver Cancer Treatment with sulforaphane significantly reduced migration and adhesion and inhibited expression of key molecules in angiogenesis, VEGF, STAT3, and HIF-1 , in liver cancer cell line, HepG2 (Sato et al., 2018)

complaints can include fatigue, weakness, weight loss, loss of appetite, nausea, abdominal pain, jaundice, itching, edema and sometimes mental confusion

Cyagens model strategy is designed around these disease-relevant mechanisms

This approach has the advantage that it integrates the effect of both genetic background and nutritional status of the cells in evaluating disease susceptibility

Consequently, the two studies have come to inconsistent conclusions